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Genes regulating the mitotic cell cycle were enriched in cluster 4 and genes regulating ion transmembrane transport were concentrated in cluster 7, which represents genes that show increased expression at later developmental stages, namely P21 and P50.
We selected a candidate biomarker from among the proteins which displayed increased expression at first.
Furthermore, these antimicrobial peptides exhibit increased expression at the transcriptomic level in fishes fed with dietary immunostimulants (Marel et al. 2012; Gong et al. 2014).
Moreover, mRNA expression levels of an ependymal NSC marker, CD133, neuroblast markers, Dlx2 and Dcx, significantly decreased in SEZ/SVZ regions of aged mice (Fig. 2E), while Gfap, an astrocyte or NSC marker, increased expression at mRNA levels.
Expression of the chaperone hspa8 showed a trend towards increased expression at 3 hours.
The MHC class I complex that has a high basal expression on non-infected cells showed an increased expression at low MOI, but its expression inversely decreased with increasing MOI in a dose-dependent manner.
IL-17 showed significantly increased expression at mRNA level after sleep restriction (138% [p<0.05] of baseline levels) and at protein level after subsequent recovery sleep (119% [p<0.05] of baseline levels).
Sixty two genes increased expression at least two-fold in response to inhibiting the V-ATPase for 24 hours, but did not respond to cholesterol deficient medium or DFO (Table S5).
Two GBSS genes showed increased expression at seed development.
CDC20 showed increased expression at 12 HAT in PI 234881.
Other genes showed increased expression at all four time points.
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