Sentence examples for increased entrapment efficiency from inspiring English sources
Drug loading and entrapment efficiency were measured by RP-HPLC method and the results show increased entrapment efficiency in F2 formulation having drug- polymer ratio of 1 3 [28].
As the surfactant content increased, entrapment efficiency increases which could be due to formation of stabilized nanoparticles.
We used a double emulsion technique to encapsulate siRNA into stealth liposomes (SL) to increase entrapment efficiency compared to passive encapsulation.
Presence of guar gum and glutaraldehyde crosslinking increases entrapment efficiency and prevents the rapid dissolution of alginate in higher pH of the intestine, ensuring a controlled release of the entrapped drug.
To increase entrapment efficiency, Landen Jr. et al. developed a method of formulating 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine- (DOPC-) encapsulated siRNA liposomes that involves dissolving DOPC and siRNA in excess tertiary-butanol in the presence of the nonionic detergent Tween 20 [ 16].
Results showed that incorporation of stearylamine resulted in an increased entrapment of fluconazole, whereas incorporation of dicetyl phosphate decreased the drug entrapment efficiency.
Complexation increased the entrapment efficiency and improved the anticancer activity.
Figure 1E,F shows that the increase in volume ratio of organic solvent phase to external aqueous phase can increase the entrapment efficiency, which may be due to the fact that the organic solvent phase acts as a disperse medium.
Drug lipid ratio is a vital parameter because higher lipid phase increases the entrapment efficiency; however, an upper limit is important to maintain the size of nanoparticle in a reasonable range.
As the drug concentration or drug to polymer ratio increases the drug entrapment efficiency increased.
This can be attributed to increase in viscosity of organic phase with increase in the PLGA amount and thus leads to slower diffusion rate of PLGA solution in aqueous phase and formation of larger-size droplets which is also related to increased drug entrapment efficiencies (EEs).
