Sentence examples for increased efficacy for from inspiring English sources

Bucindolol is a non-selective beta-blocker with mild vasodilator activity previously found to have accentuated antiarrhythmic effects and increased efficacy for preventing heart failure events in patients homozygous for the major allele of the ADRB1 Arg389Gly polymorphism (ADRB1 Argenotypegenotype).

Second, the D74N mutant shows impaired G protein-dependent signaling, which is restored to full length WT levels upon truncation, and shows >20 fold increased potency and increased efficacy for β-arrestin2 recruitment in response to SII AngII.

Few studies have examined different dosage regimens of moxifloxacin, though one demonstrated increased efficacy for 400 mg vs. 200 mg [ 18].

Both trials failed to find a significant clinical benefit with the addition of celecoxib to the exemestane regimen, despite earlier indications in small feasibility studies that there could be increased efficacy for the combination [ 13, 14].

Pre-clinical studies in ovarian cancer xenograft models have shown increased efficacy for the combination of VEGFR and PDGFR tyrosine kinase inhibitors associated with decreased vessel coverage by pericytes supporting PDGF signalling as an antiangiogenic therapeutic target (Lu et al, 2007).

LDL incorporated OL-NME enhanced the anti-tumour activity against murine B16 melanoma model; this resulted from increased efficacy for OL-NME-LDL at doses equal to free 9-OH-NME (157 vs 76 of Increase Life Span (ILS) values after intraperitoneal (i.p).

The mission, according to AirPR's founder, is to decrease the friction for the PR professional, while increasing efficacy for the client — a mission that, if it is followed-through, could bring a huge benefit to startups and big companies alike.

Higher doses did not appreciably increase efficacy for a given dose cohort.

42 Alternatively, if the target audience is in danger control, messages can remind people about the threat of smoking to maintain motivation, while also increasing efficacy for quitting, as above.

In addition, this same mutation increased efficacy of cytisine for the A3B2 receptor from 7%to16%6% (Table 3).

Therefore, the concept of treatment intensification could be associated with a significantly increased efficacy of glass microspheres for lesions larger than 5 cm.