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The increased edema after SMF-exposure indicated an increased tumor microvessel leakiness possibly enhancing drug uptake.
Histologic evaluation revealed increased edema, neutrophil infiltration, and muscle-fiber necrosis in L-NMMA-infused EDL, compared to the controls.
Hetero- and homozygous PACAP knockout animals had increased infarct volume with increased edema formation and more severe neurological deficits after MCAO, and these could be ameliorated by PACAP injection [40, 71].
Whereas injury in more mature animals led to the development of enlarged alveoli, increased edema and abnormal abundance of elastin with only minor fibrotic changes, more immature animals developed dysmorphic microvasculature and varying degrees of fibroproliferation [30,31].
Increased edema formation was recently reported in the inflamed skin of Vasp−/− mice [18] and hypoxia has been shown to foster vascular leakage by downregulation of VASP in vitro [28].
The reduction in oxygenation can be attributed to increased edema and atelectasis.
Similar(33)
Smoking induces narrowing of the oropharynx in the upper airway by increasing edema and thickness of the uvular mucosa, which may be the most common mechanism underlying the increase in OSAS severity31.
If capillary permeability is altered, increased blood flow may induce or increase edema.
First, one should exert caution when patients are in a lateral decubitus position since the gravity-induced flow diversion may increase edema formation if capillary permeability is increased.
We assessed whether increasing edema accounts for the well-known worse prognosis of glioblastoma with increasing age [ 12].
Increasing edema and enlargement of infarct lesion may be frequently observed, especially if the lesion is large.
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