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An increased dose-dependent manner was found for the NSA and RP values of the CTX and CTX/HP-β-CD complex.
The extracts also showed increased dose-dependent antihyperglycaemic effect.
Epidemiological studies also found an increased dose-dependent relative risk of cancer in exclusive users of insulin glargine [ 7, 8].
The duration and number of cordless and cellphone calls consistently indicated an increased, dose-dependent risk of suffering from headache.
Finally, the iron donor, lactoferrin, led to increased dose-dependent adipose tissue release of RBP4 (2.4-fold) and increased RBP4 expression, whereas apotransferrin and deferoxamine led to decreased RBP4 release (23).
KB 8-5 cells treated with different doses of MG-132 and daunorubicin (10 μM) for 45 minutes showed increased, dose-dependent accumulation of daunorubicin in the cytoplasm (e.g. a 4-fold increase at 50 μM MG-132, Fig. 3) indicating that MG-132 could block P-gp function.
A meta-analysis by Little et al 10 combining morbidity and mortality studies of occupationally and environmentally exposed populations with mean dose below 0.5 Gy demonstrated significantly increased dose-dependent risk for ischaemic heart disease, cerebrovascular diseases and other circulatory diseases.
The scavenging of NO was found to increase in dose dependent manner (Fig. 4).
With the increasing dose of Cd, H2O2 content was increased in dose-dependent manner.
Urine output and sodium excretion increased in a dose dependent manner.
The accumulation of cells in G2 increased in a dose dependent manner.
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CEO of Professional Science Editing for Scientists @ prosciediting.com