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Increased divergence of maternally expressed genes might have its cause in increased mutation rates, reduced purifying selection, or positive selection.
More important, these nodes showed an increased divergence of within/between-module connections, which were defined as a differential functional connectivity.
The repeated spells of cooling in the Pleistocene could also have increased divergence of the genetic lineages in this environmentally sensitive species.
Increased divergence of DNA and protein sequences (p < 0.03) and elevation of Ka (p < 0.03) of maternally expressed genes became slightly more significant.
Comparisons with other species, for which fewer sequences of imprinted genes are available, show a tendency towards increased divergence of murine imprinted genes as well (additional file 2).
In a previous study, we concluded that the increased divergence of maternally expressed genes occurred most likely due to reduced selective pressure [ 31].
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Chromosome IV is of particular interest, as the gene related to lateral plate number variation – Ectodysplasin A (eda) [ 46] – is located within a genomic region of increased divergence on this chromosome.
Piketty focuses on the increasing divergence of the income and wealth distributions between the top percentile and everyone else.
However, it is also possible that with the increasing divergence of genomes, gene replacements increasingly involve metabolic, signal transduction, and other gene modules, so that selection becomes relevant only for the conservation of the core genes that largely encode components of information processing systems.
This trend may reflect increased divergence rates of this class of proteins.
Here, we present the first demonstration that experience can drive an increase in input strength via increased divergence independent of the strength of individual connections.
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