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This raises the possibility that control populations had a small number of mutants or persister clones, which emphasized the necessity of confirming that the resistance of selected library clones was due to increased copy of plasmid-based genomic insert DNA.
We obtained the complete mt genome of the oguC devoid of cox2-2 and increased copy of atp9.
One increased copy of A in rs7865618 is associated with a 7% increase in the ANRIL transcript ENST00000428597 on the log2 scale, which corresponds to a 5% increase on the original scale.
Although many of the phenotypes are shared between the mice, an increased copy of APP is not sufficient to recapitulate all of the AD-related phenotypes of Down syndrome mouse models.
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Both LP-gp and HP-gp cells contained increased copies of the MDR1 gene.
In all, 18 (38%) hormone-sensitive tumours and 23 (47%) hormone-relapsed tumours (P=0.46) had increased copies of the X chromosome (Table 2).
Most LCSCs displaying high levels of EGFR expression and activation (LCSCs 3, 4, 5) harbored increased copies of EGFR gene (>8), suggesting that increased EGFR gene copies may contribute to overexpression and consequent activation of the receptor (Table 1).
A positive linear regression coefficient indicates that increasing values of the quantitative outcome are associated with increasing copies of the minor allele in the genotype.
3q22) in the regression on TIBC, indicating that increasing values of TIBC are associated with increasing copies of the minor allele in the rs3811647 genotype.
22q11) on TIBC, the parameter estimate was negative, indicating that decreasing values of TIBC are associated with increasing copies of the minor allele.
We observed association (additive model) between DKK1 SNP rs1569198 and dehydroepiandrosterone sulfate (DHEAS), with increasing copies of the A allele correlating with increasing DHEAS (AA: 2229.0 (1551.3), AG: 2099.0 (1373.8), GG: 1978.0 (1520.0) nmol/l; P = 0.05).
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