Sentence examples for increased colitis severity from inspiring English sources

Most strikingly, a detailed culture-based comparative analysis of the intestinal flora demonstrated that E. coli concentrations increased to a lesser degree in DSS-treated TLR2- and TLR4-deficient animals as compared to wt mice (P<0.01), indicating that increased colitis severity is associated with higher E. coli loads (Figure 5A).

Interestingly, a study demonstrated that while Smad7 overexpression in T cells increases colitis severity, it decreases colitis-associated cancer (Rizzo et al., 2011).

In contrast, Nlrc4−/− mice did not exhibit increased colitis and tumorigenesis (Allen et al., 2010).

Data on LGR4 show similar effects on gut homeostasis, it's disruption in mice leads to diminished Paneth cell numbers as well as increased DSS colitis severity (Liu et al, 2013).

Interestingly, absence of AhR ligands increased severity of colitis in mice; when animals were fed with diet enriched in AhR ligands, observed alterations were reversed.

Gpa33 –/– mice exhibited hypersensitivity to food antigens and a markedly increased severity of colitis upon exposure to DSS.

Although global colitis severity was exacerbated in this experiment, we re-observed an increased mortality among the group of transferred mice fed with Nissle ∆clbA as compared with the group of transferred mice fed with Nissle WT (Fig. S3B ).

Colitis severity eventually resulted in death of the animal (6.6%) and an increase of mortality especially in animals fed with Nissle ∆clbA (19%) that led us to abort prematurely the experiment at day 45 (Fig. 3B).

Visible colitis severity, colon/body weight ratio and myeloperoxidase activity were measured as inflammatory indices.

For example, mast cell-derived mediators can contribute to colitis severity by enhancing neutrophil influx and thus perpetuating ongoing inflammation.

Colitis severity assessed using a Disease Activity Index.