It has previously been shown that spt-11 plants have larger leaf areas due to increased cell number [ 21] and cotyledon size due to increased cell expansion [ 23].
Thus, the increased leaf size of the PdGAUT12.1-KD lines is due to both increased cell number and cell size.
Relative cell growth refers to increased cell number normalized by cell number prior to PMA treatment.
A previous report by (Song et al. 2007) described that loss of GW2 function increased cell number resulting in wider spikelet hull.
In contrast, retinas of space-flown animals showed greater GFAP immunoreactivity associated with both an increased cell number and a higher thickness of intermediate filaments.
However, total triglyceride levels per well increased with a concentration-related trend for all compounds, likely due to the increased cell number.
Cellular studies showed increased cell number, viability, and osteogenic differentiation on the porous polymers compared to solid block polymers (P < 0.05).
In summary, all perfluorinated compounds increased cell number, decreased cell size, increased total triglyceride, and altered expression of genes associated with adipocyte differentiation and lipid metabolism.
Exogenous BDNF also increased cell number in TrkB/p75 compared to TrkB cells (p < 0.01), due to an increase in proliferation, but without differentiation.
Our data suggest that the increased cell number is the primary reason why cultures grown on 3M™ESPE™ MDI deposited more minerals in comparison to those grown on Ankylos®.
Furthermore, data from histological analyses of spikelet hulls before heading suggest that loss of GW2 function increased cell number, and thus the wild-type GW2 negatively regulated cell division by targeting its substrate(s) to proteasomes for proteolysis [67].
