Sentence examples for increased cell cycle from inspiring English sources

F + RT leads to a decrease in the surviving fraction, increased cell cycle arrest, down regulating of nonhomologous repair protein DNA-PKcs and homologous recombination repair protein RAD51.

Gene ontology (GO) analyses of these genes indicated that aged cells had increased "cell cycle arrest", increased "cellular response to stress", increased "ER overload response", and decreased "cell cycle" (e.g., Melk, Mapk3, etc).

We demonstrated that NP AR-shRNA enhances PCa radiosensitivity as indicated by the inhibition of cell growth, increased apoptosis, and increased cell cycle arrest in AR-dependent HIPC in vitro.

On the other hand, overexpression of stabilized β-catenin in cortical precursors leads to increased cell cycle re-entry and subsequent overproduction of neurons [7].

EGF treatment of ER-negative breast cancer cells also led to NFκB activation and indirectly, through increased expression of cyclin D, increased cell cycle progression [47].

Compared to Gfi1+/+ HSC, Gfi1−/− HSC gave rise to slightly increased numbers of CFU (8750 versus 6650) when incubated in the presence of IL3, SCF, Flt3L, IL6, potentially reflecting increased cell cycle progression in Gfi1−/− HSC (13).

The mitotic arrest of Nde1−/−Lis1+/− progenitors was followed by a drastically increased cell-cycle exit.

Recently, we reported about the activating effect of interferon- α (IFN α) that directly acts on murine HSCs and induces increased cell-cycle activity (Essers et al, 2009).

In another example, our studies in human biopsies from patients with liver fibrosis revealed increased cell-cycle activity of hepatocytes and HSCs that was associated with elevated expression of cyclin E1 and the proto-oncogene c- myc[ 211, 212].

HF diet induced early changes in gene expression associated with increased cell-cycle progression, proliferation and differentiation of islet cells, and oxidative stress (e.g. Cdkn1b, Tmem27, Pax6, Cat, Prdx4 and Txnip).

Assessment of cycling characteristics of the CD34+CD38−CD90+ HSC-enriched fraction showed a 2.8-fold increase in the fraction of cells in S/G2/M upon 126/KD, indicating that the observed expansion coincides with increased cell-cycle progression.