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The expansion of the database of mimotope sequence motifs can be increased by analyzing structures that bind to HIV directed monoclonal antibody 2G12 and the lectin Concanavalin A (Con A), fostering new mimotope designs.
Resolution was not increased by analyzing whole sequences or just the Zn-fingers (not shown).
However, the clinical significance of DTC-status at primary surgery was not increased by analyzing more cells in our previous study [ 34].
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This enrichment procedure allows for increased sensitivity, by analyzing a 5 10 fold larger volume of blood, compared with a direct immunocytochemical (ICC) technique, with minimal impact on laboratory workload.
Finally, initiation interrogates one method with another; it increases depth by analyzing findings and interpretations from the perspective of different methods and paradigms.
We assessed the increased collection efficiency by analyzing the energy content of the images from each frame.
The ROC curve for the phastCons predictions is displayed alongside the BigFoot ROC curves in Figure 3. Comparing the AUC values demonstrates how the increase in predictive accuracy caused by adding more sequence data is less than the corresponding increase caused by analyzing a distribution of alignments instead of a single alignment.
It is possible to increase the sensitivity by analyzing larger number of cells (higher BM-volume).
As observed by optical microscopy, cell superficy was significantly increased by 5.3-fold (p<0.005 analyzed by Metamorph software) in newly confluent Caco-2/15 cells expressing shPTEN compared to control cells (Figure 1B, left panels).
This suggested that the cell speed increased, which was confirmed by analyzing the nuclear displacement rates.
To provide site-specific estimates of the evolutionary processes underlying the rapid evolution of five of our candidate fast-evolving sex-associated genes, we increased our statistical power by analyzing the genes from additional species of Neurospora (Additional file 2: Table S2), again applying the maximum likelihood program codeml included in the PAML package version 4.3 [ 32, 33].
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