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Several studies find no evidence that increased breast size is associated with increased risk of breast cancer (Wynder et al., 1960; Katariya et al., 1974; Kolonel et al., 1986; Senie et al., 1993; Koch et al., 2004), while others found indications of a positive correlation (Scutt et al., 1997; Hsieh & Trichopoulos, 1991; Joensuu et al., 1992; Kato et al., 1995).
The detection of a breast tumour is known to be impeded among obese women assuming that increased BMI is a proxy measure for increased breast size.
An increased breast size moved women towards the socially constructed ideal, increasing body image satisfaction [ 26], whereas changes such as acne or stretch marks moved them away from this ideal [ 26, 30].
Lactation, of course, leads to increased breast size, which explains its appeal to some, says Rebecca Kukla, an ethicist who's written on cultural perceptions of breastfeeding.
However, if a minimally invasive option were to become widely available, it would offer women reluctant to undertake the risks of surgery the opportunity to achieve moderately increased breast size.
Increased breast size should be an added bonus, not a main incentive.
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In the present study, the rs10736393 G allele was significantly associated with increased breast cancer risk with an effect size of rs2981579 that was the same as in a previous report [ 8].
These findings are in agreement with the known correlation between increased breast cancer mortality risk and increasing tumor stage, size, grade, or regional lymph node metastases [ 18, 19].
However, a larger breast size has been associated with increased breast cancer risk (Kato et al, 1995), especially in lean women (Kusano et al, 2006) or in women with proliferative breast disease (Dupont and Page, 1987).
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