Sentence examples for increased aromatization from inspiring English sources

This generally supports the concept of increased aromatization in synovial tissue under inflammatory conditions.

Increased aromatization of androgens into estrogens takes place in adipose tissue.

First, it stimulates aromatase expression and, as a consequence, elevates estrogen levels via increased aromatization of androgens.

Males may also develop gynecomastia when the estrogen/androgen ratio is increased due to decreased androgen production or increased aromatization.

Interestingly, increased aromatization of androgens to estrogens has been demonstrated in cultured synovial cells from RA patients [ 32, 33].

Increased aromatization of androgens into estrogens in fat tissue leads to elevation of concentrations of endogenous estrogens.

Increased testosterone aromatization to estradiol in flutamide-treated boars [ 34] could also contribute to enhanced Cx43 expression in prostatic cells as shown by Carruba et al. [ 53].

Accordingly, exogenous androgen increases aromatization to estradiol, which leads to increases in serotonin synthesis and availability via estrogen receptors (58).

Obesity in postmenopausal women enhances circulating levels of estrogen through increased production and aromatization of androstenedione in adipose tissue, as well as decreased production of sex-hormone-binding globulin and reduced 2-hydroxylation of estradiol [7].

Our postulate is based on the speculation that the potency of binding will be increased upon cyclo-aromatization reaction due to increased π-stacking interaction.

One of the proposed mechanisms is that increased estrogens due to aromatization of androgens in the adipose tissue can hamper fertility (25).