Sentence examples for increased activity against from inspiring English sources

First-generation cephalosporins (cephalexin, cefadroxil) are predominantly active against Gram-positive bacteria, and successive generations have increased activity against Gram-negative bacteria (cefoperazone) [1 3].

The third-generation cephalosporins (ceftriaxone, cefixime, and ceftazidime) have increased activity against the gram-negative organisms compared with the second-generation agents.

Among the LigI-selective inhibitors, L82-G17 exhincreasedcreactivityivity against and selectivity for LigI compared with L82.

Both analogues showed an increased activity against HL-60 cells with 17- and 185-fold higher potency than -muricatacin.

Generally, introduction of hydrophobic moieties at the N-terminus resulted in analogues with remarkably increased activity against multidrug-resistant Staphylococcus aureus and Enterococcus faecium.

Herein, using a cell based assay that we developed, we identify two new aminoadamantyl derivatives that show increased activity against otherwise resistant M2 variants.

Using an X-ray crystallography/structure-based design approach, the benzomorpholinone series was further optimised, increasing activity against T. brucei NMT by >1000-fold.

If not, could it be that the sequence context of R1-11 promotes improvements towards 2-phenoxyethanol because of some specific position on the neutral network that elevate the chances of increasing activity against 2-phenoxyethanol?

The main flaw is that small structural changes can lead to a dramatic change in property (e.g. changing a hydrogen bond donor for an acceptor activity can greatly increase activity against a target), which has a major impact in studying quantitative structure activity/property relationships[ 15].

Increased activity of TRAIL against resting tumor cells might explain why TRAIL is especially effective in combination with cytostatic drugs, which induce cell cycle arrest.

One possibility is that increased plasmalogens may be an indication of increased activity of protective mechanisms against oxidative stress (Barr et al., 2012).