Sentence examples for increase transposition from inspiring English sources

Use of a more efficient transposase could also increase transposition efficiency.

A side effect of the rearrangement process is the large increase in the size of the inverted repetition, which may increase transposition ability by stabilizing the synaptic complex.

While the SB10+/+ seed male did not show increased transposition over other independently generated seed mice for the 4563 line, there was an increase over its sibling SB10+/- seed male, suggesting that we may be able to increase transposition rates by increasing the transposase dosage in future studies.

Modifications are described in the Materials and Methods and include an upgrade to the 'T2' versions of the SB inverted terminal repeat sequences (ITR), demonstrated to increase transposition activity in vitro [ 14], and the addition of stop codon sequences in each reading frame just upstream of the IRES.

Although Agrobacterium infection has previously been shown to increase transpositions, earlier studies were conducted using non-oncogenic strains harbouring T-DNA and vir genes [ 12].

However, the heterochromatic state can potentially silence promoter activity, which would mitigate the advantage of increased transposition.

Recently, other groups have shown that Hp1a localizes to Drosophila and mammalian telomeres and that mutations in Hp1a increase the frequency of telomere fusions and cause increased transposition rates of both HeT-A and TART elements[69], [70].

Transposition efficiency is directly dependent upon increased transposase levels up to a certain threshold level [37]; therefore, our results may reflect this increased transposition efficiency and a corresponding deleterious effect on viability due to increased integration events with higher probability of disrupting essential genes and/or regulatory elements.

The WGD possibly increased transposition and chromosomal breakages leading to the relocation of genes.

However, increased transposition rates can also lead to an accumulation of deleterious mutations in the genome.

Since zero copies is an absorbing boundary, increasing transposition via λ(t) speeds up the extinction of ISs through increased K.