For example, individual Iberian wall lizards (Podarcis hispanica) which habituate more rapidly to a non-threatening stimulus, increase their body condition (a correlate of fitness in the species) more rapidly than individuals that habituate less [ 46].
This is in contrast to neurons in the trigeminal ganglion, which can increase their firing output with increasing stimulus intensity across a broader range (Shoykhet et al., 2000).
The updating or remapping is hypothesized to work in the following way: upon appearance of a stimulus, neurons with RFs covering the stimulus' position increase their activity.
Thus, SCs exposed to a combination of matrix and necrotic stimuli increase their production of inflammatory cytokines that have defined roles in myoblast function and maturation.
IgE and Fc εRI engagement can also decrease the release threshold of mast cells and increase their sensitivity to various stimuli through either Fc εRI or other receptors for the degranulation process [ 11, 12].
This observation is borne out by measuring the capacity of the NK cells to increase their response from a weaker stimulus (Huh7.5 plus 50 IU/ml IFNα) to that of a stronger stimulus (K562 plus 1000 IU/ml IFNα); this increase is calculated as a functional ratio=% CD107a+ with strong stimulus÷% CD107a+ with a weak stimulus (as outlined in the Methods section).
Visual neurons, which are responsive to the weak visual motion-direction signals, may thus increase their responses to this visual stimulus via the learning signal and in doing so improve sensitivity to that motion-direction.
During central sensitization, nociceptive-specific neurons may progressively increase their response to repeated nonpainful stimuli, develop spontaneous activity, and increase the area of the body that is involved with the pain [36].
During central sensitization, nociceptive-specific neurons may progressively increase their response to repeated nonpainful stimuli, develop spontaneous activity, and increase the area of the body that is involved with the pain [ 36].
In terms of sympathetic control of inflammatory arthritis a possible approach is to follow the success seen in animal models and put effort into developing novel cellular therapies; for example, after induction of TH in certain immune cells or treatment of B cells with sympathetic stimuli to increase their regulatory potential.
