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Sequential coupling between COPII and COPI vesicles is important to coordinate and direct bi-directional vesicular trafficking between the ER and the Golgi apparatus (Aridor et al. 1995), suggesting that improving the recycling of these components would further increase the trafficking flow to enhance protein secretion.
Notably, most known proteostasis modulators that increase the trafficking of ΔF508-CFTR to the plasma membrane (sildenafil, glafenine, genistein and curcumin) appear to be inhibitors of posttranslational modifications (Hanrahan et al, 2013).
The presence of unedited GluR2Q subunit can have dramatic downstream effects as it can increase the trafficking of GluR2 subunit to the synapse as well as increasing the permeability of AMPA receptors to calcium ions.
Similar(57)
Additionally, the proposed mall would substantially increase the traffic on the already heavily congested Hutchinson River Parkway.
Our aim would be simple – to increase the traffic to, and investment in, original British content.
"It would increase the traffic very, very much and pose a danger".
Traffic congestion reduction: It turns out that by intelligently controlling the speed of a few autonomous vehicles we can drastically increase the traffic flow.
This can definitely increase the traffic of those blogs.
"It's going to increase the traffic through the village.
The line is built to increase the traffic on the west corridor.
The line was built to increase the traffic on the west corridor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com