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Urocanic acid (UCA) which is produced in the upper epidermal cell layers, also has a sunscreening role but paradoxically, absorption of UVR results in the production of a photoisomer (cis-UCA) which has immunosuppressive properties and may increase the progression of skin cancers [59].
Based on these findings, we conjecture that the absence of cystatin C also may increase the progression and growth of other types of tumors.
Oestrogen and prolactin are thought to increase the progression of murine SLE.
Likewise, mothers in Malawi [ 19] felt that exclusive breastfeeding would increase the progression of HIV.
These LMW isoforms are nuclear and functionally active because they increase the progression from G1 to S phase [ 11].
HIV coinfection has been shown to increase the progression of liver fibrosis [ 37, 38] and is likely to eventually increase the incidence of the tumor [ 33].
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It was reported that oxaliplatin based chemotherapy could significantly increase the progression-free survival in patients with metastatic CRC [ 10].
Nonspecific HIF1 α inhibitors appear to increase the progression-free survival and reduce the risk of developing CRPC and metastases in patients on continuous ADT.
The primary objective of the study was to assess whether a metronomic chemotherapy regimen including UFT plus CTX and CXB could increase the progression-free survival at 2 months in a population of metastatic gastrointestinal cancer patients already treated with several chemotherapy lines.
However, whether OSA itself initiates or increases the progression of these abnormalities is entirely unknown.
This change induces systemic inflammation and potentially increases the progression of chronic arthritis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com