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Utilization of the full detection volume would require larger T-connections and therefore substantially increase the dead volume.
They increase the dead space, which in turn decreases alveolar ventilation and leads to increase in arterial carbon dioxide tension.
In currently used ventilation modes, the inbuilt flow sensor and the gadget for closed endotracheal suction increase the dead space significantly.
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By contrast, AuNP 2-II continuously increases the dead cell ratio with time.
A slightly higher Au wt% of AuNP 2-IV increases the dead cell ratio more effectively than AuNP 1-IV.
PEG-conjugated AuNP 1-III increases the dead cell ratio with time, even with small amount of uptaken AuNPs.
The Au wt% of Spacer V is low at the initial stage, but it significantly increases the dead cell ratio with time.
Increasing the FAP density from 20 to 50% increases the dead zones from 20 to 45% of ground floor.
A large diameter increases the "dead area" created by the receiver shadow on the concentrator and the heat losses to ambient air, while a longer cylindrical creates a temperature gradient with slower heat transfer.
Therefore, in current practice we should carefully evaluate the real need, in each case, for any ventilator circuit component that actually increases the dead space of the apparatus, like an artificial nose.
Mainstream flow sensors and gas analyzers considerably increase the apparatus dead space so that high dead space fractions are not uncommon.
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