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Excited, Groopman, deciding to increase the aggressiveness of treatment, took a chest X-ray, which showed that most of the metastases were reduced by more than half.
Some examples of confounding effects are the selection of cancer cells more likely to migrate or the induction of mutations that would increase the aggressiveness of tumour cells.
The results indicated that though the pure chemo-drug treatment could reduce the size of tumor, it might also increase the aggressiveness of tumor due to the increased fraction of CSCs, especially for the tumor with the CSCs that have high self-renewal ability.
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Moreover, induction of PDGF as well as PDGFRβ expression in response to TGFβ stimulation has been recognized as an important component of epithelial-mesenchymal transition, a process that underlies metastasis of some tumors [20] and increases the aggressiveness of others [21].
Next, we examined whether Bmi-1 increased the aggressiveness of glioma cells via activation of the NF-kappaB signaling pathway.
Unlike other systemic mycoses, paracoccidiodomycosis can cause disease in immunocompetent hosts, although immunosuppression increases the aggressiveness of the fungus.
We postulated that RUNX2 may have a pathological side that increases the aggressiveness of MDA-MB-231 cells during metastasis.
Overexpression of REG4 protein increased the aggressiveness of ovarian cancer, as indicated by reduced apoptosis and increased proliferation, migration and invasion.
Therefore dNTPs pool expansion, acceleration of cell proliferation, and improvement of metastasis ability may partly explain why RRM2 increases the aggressiveness and causes poor survival in CRCs.
Our findings suggest that elevated MYO10 expression increases the aggressiveness of breast cancer; this effect is dependent on the involvement of MYO10 in invadopodial formation.
STMN-1 Up regulation increases the aggressiveness of esophageal adenocarcinoma cells, and enhances the migration ability which is responsible for metastasis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com