The heterozygote knock-out animals have total homocysteine concentrations only twice that of wild-type, compared to a difference of more than 5-fold increase that is typical of human CBS deficiency [ 43] and seen in our experimental model.
Because of anticipated call-volume increases that are typical after Labor Day — and the expected settlement news, which also would generate additional inquiries — the roughly 10,000 workers at the bank's telephone contact centers were instructed to try to process customer requests as quickly as possible.
Because of anticipated call-volume increases that are typical after Labor Day — and the expected settlement news, which also would generate additional inquiries — the roughly 10,000 workers at the bank's telephone contact centers were instructed to try to process customer requests as quickly as possible.
Remarkably, an increased Aβ42/Aβ40 ratio that is typical of AD inverted the expression pattern of NEUROG2 and KIAA0125 that was observed for a decreased ratio.
The effects of transfer of adults to SD on food intake and body weight were particularly dramatic, as they prevented the steady increase in body mass that is typical of ad lib fed rats in this age group.
As shown by FACS analysis of PI labelled cells, 0.25 µM doxorubicin did not increase the sub-G0 phase that is typical of apoptosis, but it decreased the number of S-phase cells by 66%, caused arrest in G2/M and confirmed the 2-fold increase in hyperploid cells (>4N phase) (Fig. 7A).
Increased awareness of CD symptoms that are typical in older children, as well as screening of siblings, could have contributed to the shift towards an older age at diagnosis, but the role of additional environmental factors should not be overlooked.
These fibers undergo a shift from a fast-twitch to a slow-twitch type with more sustained activity and increased resistance to fatigue, characteristics that are typical of muscles with a high degree of oxidative, fatty acid metabolism (41– 41).
We suspect, but have not proven, that there is shunting between pre-capillary arterioles and post-capillary venules, accounting for the prominent increases in mixed venous oxygen saturation that are typical of the initial stages of septic shock.
Within the last year and a half, Fidelity and Vanguard, the two largest 401(k) managers, have raised their international allocations to 30 percent of their total stock holdings from 20 percent, an increase that experts say is typical.
Sean Spicer, the RNC's communications director, said that the party's increased line of credit was typical for this point in an election year, adding that party officials were optimistic about fundraising.
