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Under sedation can cause hyper-catabolism, immunosupporession, hypercoagulability and increase sympathetic activity.
These substances exaggerate the vasospastic activity of other drugs, enhance endothelial dysfunction, increase platelet aggregation, increase sympathetic activity, and decrease the myocardial oxygen supply [14].
In rats, both these procedures are known to increase sympathetic activation of interscapular brown adipose tissue (iBAT) thermogenesis, important for heat production in the rat.
PACAP is well known as a master regulator of the stress response, acting with the CNS and peripheral nervous system to increase sympathetic activity (reviewed in [46, 68, 119, 149]).
Similarly, Carmignani et al. [27] reported that lead appears to increase sympathetic nerve activity by central mechanisms.
Furthermore, activation of neurons in the LH increase sympathetic nerve drive to BAT, in a pathway dependent on activity from neurons in the DMH [40].
Similar(25)
Model simulations reveal that vascular stiffening increases sympathetic tone and shifts the effective baroreflex response to an increased pressure baseline.
This may be driven by increased sympathetic autonomic activity.
Angiotensin II is a vasoconstrictor agent, increases sympathetic discharge and adrenal medullary catecholamine release.
These states are observed when there is hypervolemia and/or increased sympathetic tone.
Pregnancy is associated with an increased sympathetic state, which can be exacerbated by gestational conditions.
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