Sentence examples for increase spine density from inspiring English sources

For example, estrogens increase spine density in the hippocampus, and NMDA antagonists block these effects.

In the cerebellum, complex motor tasks have been shown to increase spine density in Purkinje neurons [39], suggesting a possible physical correlate for synaptic plasticity.

Notably, BDNF is known to increase spine density and the proportion of mature spines.

Conversely, Nrg1-ΔNLS expression did not increase spine density indicating that nuclear localization signal of Nrg1 is required for this function.

Importantly, a sequence variant of KALRN found in schizophrenia patients encodes a Kalirin-7 mutant with diminished Rac GEF activity, and this mutant fails to increase spine density and size [ 58].

Wild-type EphB2 overexpression increases spine density while disruption of EphB2 forward signaling results in increased filopodia density.

However, the increased spine density and synapses may keep the synaptic input constant [34] or increased as shown in the present study.

Specifically, it was shown that hippocampal CA1 pyramidal neurons of adult offspring from high LG mothers exhibited longer dendrites and increased spine density as compared to offspring of low LG mothers [12].

Wild-type mice treated with Reelin show increased spine density in apical dendritic spines.

Similar to Sema5A germline null mice, conditional Sema5A ablation in GCs leads to increased spine density.

Deletion of this receptor results in increased spine density in the neocortex (Chen et al., 2012).