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Additional PCR on obtained products was conducted with either RATZEB1 or RATZEB2 satellite specific primer, and inner adapter-specific primer to increase specificity of amplification.
This procedure has been suggested to reduce caller-specific errors and increase specificity [ 18, 58].
To increase specificity, all serum samples that indicated probable infections were further investigated with more specific ELISA techniques.
However, by making simplified versions, we hope to increase specificity and to understand the structural requirements for activity.
To increase specificity and efficacy, we have designed a synthetic antioxidant, XJB-5-131, targetget mitochondria.
Here we show that engineering a hairpin secondary structure onto the spacer region of single guide RNAs (hp-sgRNAs) can increase specificity by several orders of magnitude when combined with various CRISPR effectors.
To increase specificity without lowering the potency of retroviral expression in hepatocytes, these elements were replaced by a sequence derived from the hepatitis B virus enhancer II region.
In addition, residues outside the main ATP-binding cleft have been identified that could be targeted to increase specificity and potency.
The proposed method, which is comprised of two stages, is designed to increase specificity in the first stage and sensitivity in the second stage.
Such stricter criteria may increase specificity and reduce the sensitivity of the criteria.
Imaging methods available are not sufficient, and radio-immunodiagnostics could increase specificity and sensitivity of diagnostics.
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