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First, a greater rate of exponential growth in polymorphism incidence of STRs (prior to the change point) may reflect the greater proportional change in total allele length that occurs for STRs as they add repeats, and this might increase slippage probability more dramatically.
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Our results give further insights into the mode of microsatellite evolution, and support the assumption of increased slippage rate with increased microsatellite length and a stabilizing effect of interrupting motifs for microsatellite regions consisting of perfect repeats.
The results show that the structural efficiency of the dome improves with increasing slippage coefficient.
Results also show that the structural performance of the articulated pressure vessel can further be improved with increasing slippage coefficients.
The increased slippage and joint capacity were attributed to the tensile resistance of the anchor spike, the clamping effect provided by the anchor, and friction between the debonded FRP strip and concrete.
The use of the thin foam is not recommended as it increased slippage, despite preventing visual marks.
However, there is a minor contribution of the GC context surrounding the AARs for an increased slippage rate.
Sequencing of 33 mutated and 66 parental HrU10 alleles was consistent with the hypotheses that longer alleles tend to be more instable due to increased slippage rate.
Our premise was that the presence of polymorphism at repeats with a certain number of units reflects their increased slippage rates.
Furthermore, ectopic expression of Mcl1 in control cells increased slippage and reduced death in DME-treated cells, recapitulating the effect of Ras activation.
Xu et al. [ 49] showed a constant slippage rate for expansion and an increasing slippage rate for contraction with increasing allele size, which is consistent with a general observation of an upper size limit for repeated regions.
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