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Although sperm-to-sperm attachments can increase progression in vitro, such attachments also prevent rolling.
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Therapies that prevent or resolve subpial lesions may be very important in treating secondary progressive MS patients as increased progression in disability is associated with cortical atrophy, and subpial lesions are represented to a greater extent than leukocortical lesions in the total cortical lesion load.
We have seen in Figure 10, that AQP3 has a reduced expression with increased progression in our melanoma dataset.
Because chondrocytes from two of thirteen different human donors responded to IL-1β with robust CHOP expression, it remains to be determined if increased CHOP expression in cartilage is a biomarker for increased progression in evolving OA.
With increasing progression in the treatment of HIV disease especially with an increasing proportion of HIV infected women receiving combination ART throughout pregnancy, modifications in the interventions to reduce HIV-1 MTCT have occurred e.g. a more tolerant approach to vaginal delivery for women who achieve significant viral suppression is now recommended in most guidelines [ 4].
We used Vokurka et al.'s [18] rule that a volume change of more than 13% is considered an increase (progression) or a decrease (regression) in size.
In breast cancer, an unplanned analysis of 3-year interim data from the Preoperative Epirubicin Paclitaxel Aranesp (PREPARE) study (733 chemotherapy patients) reported increased mortality and increased disease progression in ESA-treated patients (Amgen, 2007).
Anti-angiogenic therapies increase progression-free survival in many tumour types and overall survival in a few tumours, but this is variable.
To determine whether an increase (or progression) in the degree of malignancy according to cytologic or histopathologic criteria corresponded with failure of intraocular melanoma control.
As HAART appears to increase fibrosis progression in HIV/HCV co-infected patients possibly through cumulative hepato-toxicity, specific treatment for HCV infection will be required to slow the growing epidemic of end-stage liver disease in this population.
A phase II trial with TRO did not increase progression-free survival in 25 colorectal cancer patients [ 43].
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