Sentence examples for increase perk from inspiring English sources

Second, the presence of CN-A appeared to increase PERK phosphorylation levels.

Additional analyses are required to determine how GSI increase pErk and pAkt in CRC cells.

Although the levels of total ERK protein did not increase, pERK levels were significantly elevated (2 4.5-fold) with respect to control cells 30 min after IGFBP-2 4.5-foldration.

In wild-type K-Ras harbouring Hkh-2 cells and c-Met normal HCC827 cells, PI103 treatment did not increase pERK, while PI103 did in their K-Ras mutant and c-Met amplified counterparts.

By contrast to IRE1 however, for which IPA drives activation in vitro and in vivo as IPA concentrations were increased, PERK activation displayed a bell-shaped dose response: PERK was activated at low IPA concentrations while being inhibited at higher ones.

Allicin markedly increased PERK and Nrf2 expression in the hippocampus.

Sindbis virus infection also induced ER stress in mammalian cells as detected by increased PERK phosphorylation and ATF4 translation.

Melanoma patient FNA samples showed increased pERK and pS6K levels in BRAF mutant compared with BRAF WT melanomas, with μNMR blood circulating tumor cell level increased with higher metastatic burden visible on imaging.

When 4T1 cells were treated by 20 ng/ml EGF for 60 minutes increased pERK expression was observed (Fig. 1a).

This hypothesis is supported by our observation of increased pERK cell counts in the PVN of females exposed to defeat.

Most LSK cells increased pERK levels in response to Thpo, yet a substantial minority of CD34+/CD34− LSK cells did not respond (Figure 3A).