Sentence examples for increase of trail from inspiring English sources

In hypoxia, such a TRAIL repression was removed and an increase of TRAIL expression was induced.

AML1/ETO binding to TRAIL promoter was paralleled by the increase of TRAIL transcription, as determined by either RT-PCR or Q-PCR.

When we applied siRNA to knockdown IRF-1, IRF-3, or IRF-7 gene expression in human macrophages, the increase of TRAIL expression by HIV-1 infection was reduced by the IRF-1 and the IRF-7 knockdown, but not by the IRF-3 knockdown (Fig. 4G).

Of note, Unnithan and Macklis documented an increase of TRAIL expression in patients treated with radiation for lymphoma [ 47].

As TRAIL is mainly expressed on immune cells and obesity is associated with macrophage infiltration into adipose tissue, we expected an increase of TRAIL with increasing BMI.

These results combined to our previous study [ 32] could suggest an incremental increase of Trail expression from BOV to LMP, LG, G2 and G3 tumors.

Furthermore, inhibition of XIAP resulted in an increase of TRAIL-induced apoptosis in HCT116 wt cells and, more importantly, overcame TRAIL-resistance of Bax/Bak double-deficient cells.

Although Song et al. suggested that NF- κB-mediated increase of TRAIL-R2 accounts for the sensitization to TRAIL by ABT-737, we observed no differences in TRAIL-R2 surface levels upon treatment with ABT-737.

Actually, irradation resulted in an increase of TRAIL-R2 expression in clearCa-22 (which does not harbour mutations in p53-coding regions), thereby possibly rendering this cell line more sensitive to TRAIL-induced apoptosis.

It is known that one of the biological properties displayed by cytokines, regardless of their biological role, is redundancy, and we have shown that the increase of tissue TRAIL expression in a murine model of spinal cord injury is paralleled by an increase of both tissue TNF- α and FasL expression.

TRAIL-selected cells (A-375-TS) revealed resistance even at increased concentrations of TRAIL and did not exceed a plateau of 6% apoptosis in response to TRAIL.