This is not simply due to an increase in absolute numbers, but also the rate of increase of expenditure on cancer.
The ICD-9CM coding system for administrative purposes might be a reliable indicator for the actual clinical risk described in existing literature and predict an increase of expenditure.
A qualitative-quantitative design including pre and post phases leads to a marked increase of expenditure and duration of a study, but also enhances the applicability of the study results for health policy makers.
In the USA, oncology medicines expenditure rose four fold in seven years [ 2] while in Cyprus, we observed a two fold increase of expenditure from 2005 to 2011 [ 3].
However, the number of young people with intellectual disability participating in open employment has remained stagnant over this same time period [ 23], regardless of the reported 47% increase of expenditure on employment services since 2005 [ 22].
Based on randomly-sampled cases from Taiwan's NHI data, the direct medical cost of one ED visit in Taiwan averaged NT$1,792 (US$54.3) for insurers in 2004, and the annual increase of expenditure for emergency medicine was estimated to be 4.9% (p < 0.001).
An increase of mitigation expenditures alleviates future temperature increases, which in turn reduces damage to the economy.
According to Giaccotto et al. [39] a 10% drug price increase corresponds with a 5.8% increase of R&D expenditures.
Almost all European countries have, therefore, developed healthcare reforms in an effort to constrain the constant increase of healthcare expenditures in the last 10 years [1, 2].
