Histomorphometric studies have stressed a discrepancy between cortical and trabecular bone with an increase of bone remodeling.
Histo-morphometric studies have stressed a discrepancy between cortical and trabecular bone with an increase of bone remodeling.
[5] found that incadronate causes a decrease in resorption, but there was significant increase of bone volume only in the group treated with high doses 4 weeks later.
Intermittent (once-daily) doses of teriparatide seem to stimulate osteoblast activity and therefore result in a net increase of bone formation.
The rapid increase of bone volume fraction in the initial growth phase can be explained by the enormous weight increase of the pigs.
At 42 months after implant insertion, continuous increase of bone volume above the implant apex was confirmed without excessive marginal bone loss around the implant neck (Figs. 6c and 7c).
Investigation has demonstrated that the use of (Sr-MBG) leads to the increase of bone formation (46.67%) in comparison with non-alloyed glass MBG (39.33%) and control group (17.50%).
After two years of treatment both patients show an increase of bone mineral density of the lumbar spine with a z-score from – 2.4 to -2.0 and -4.3 to 2.5 respectively and an increase of projected vertebral area L2 – L4 [mm²] from 1670 to 2152 and from 1424 to 1528.
Studies carried out by Becker et al. [16] revealed that local application of diverse growth factors (IGF-I and PDGF) induce the statistical increase in bone repair and the increase of bone density, around Ti implants, compared with the control group.
Medial and lateral condyle from the control group did not differ significantly, while medial condyle from OA group showed a high increase of bone volume (62.8 ± 13.3) and consecutively different trabecular parameters when compared with the lateral condyle from the same group.
Importantly, implants in rabbit femur show a significant increase of bone growth and bone-to-implant contact in the case of the collagen modified samples, confirming that biochemical modifications of Ti surface can enhance the rate of bone healing as compared to plain Ti.
