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Movement by swimming, walking, and shivering are three mechanisms for increasing metabolism; a fourth process involves an increase in the breakdown of fats by enzymes, which is induced by the hormone glucagon.
During acute physiological stress, the metabolism is altered, as an increase in the breakdown of fat (the lipolysis) due to adrenergic mechanisms (Hagstrom-Toft et al. 1993).
Our findings show that ovariectomy induces a significant increase in the breakdown of collagen type II and subsequent articular cartilage erosion.
Aside from the de novo synthesis of PC, two other potential mechanisms could contribute to PC accumulation: a decrease in the further metabolism of PC via CCT and an increase in the breakdown of PtdCho.
Examination of this pathway reveals three sources that could be responsible for increased PC following 17-AAG treatment: an increase in the de novo synthesis of PC from extracellular choline, a decrease in the further metabolism of PC via CCT, or an increase in the breakdown of PtdCho.
Several possibilities have been proposed including (i) a reduction of the endogenous NO synthesis by feedback inhibition due to the high concentrations of NO contained in the cigarette smoke [ 9] (ii) an inadequate supply of cofactors necessary for NO production [ 25] and (iii) an increase in the breakdown of NO [ 26].
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In patients with type 1 diabetes, insulin deficiency, if not recognized and treated properly, leads to severe hyperglycemia and to a marked increase in lipolysis (the breakdown of lipids), with a greatly increased rate of release of fatty acids from adipose tissue.
In patients with type I diabetes, insulin deficiency, if not recognized and treated properly, leads to severe hyperglycemia and to a marked increase in lipolysis (the breakdown of lipids), with a greatly increased rate of release of fatty acids from adipose tissue.
Excluding Cdc24, disruption of any of the other NOX complex components resulted in hyperbranched hyphal growth within ryegrass leaves, which no longer aligned parallel to the leaf axis as well as increased fungal biomass resulting in the breakdown of a mutualistic interaction and the development of pathogenesis (Fig. 6B).
The largest effect was a 1 V increase in the breakdown potential at a silicate concentration of 0.025 M.
Necrotic cells present pale eosinophilic cytoplasm, swollen nucleus, euchromatic chromatin that condensates into irregular patches and increased cell volume that culminate in the breakdown of the plasma membrane (Fig 4).
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