Your English writing platform
Discover LudwigExact(40)
Compared to pyrosequencing, the dominant sequencing technology in metagenomics, our composite read strategy already provides a >30-fold increase in sequencing capacity per dollar at similar or higher accuracy (Table 2).
At higher concentrations there was an increase in sequencing errors, while lower concentrations reduced the sequencing signal.
Fitting these statistical methods is computationally expensive, and will not scale as the increase in sequencing throughput continues.
Generally speaking, with the MiSeq an approximately 70-fold increase in sequencing depth led to an at least 3-fold decrease in the background noise.
DNA extracted from FFPE samples frequently contains lesions such as abasic sites that lead to a significant increase in sequencing errors when using traditional single-strand sequence capture methods [ 9].
These limitations are starting to be overcome thanks to the increase in sequencing depth of Hi-C data 5 and the up-scaling of Chromosome Conformation Capture Carbon-copy (5C) to span large regions 11.
Similar(19)
Our knowledge of the diversity of this protease family in nematodes is aided by the rapid increase in sequence information, especially from the Brugia malayi genome project.
In all age groups, there was a significant increase in sequence homology flanking the deletion compared to mtDNA background.
Furthermore, an increase in sequence length generally leads to a smaller variance in evolutionary rates and other parameters in model-based phylogeny-reconstruction methods.
For 21 patients we could observe an increase in sequence divergence with decreasing CD4+ T-cell count to the immunodeficiency level - below 200cells/mm3 (example in Figure 10A).
Our data reveal that, regardless of the presence of a direct repeat, most mtDNA deletion regions have a significant increase in sequence homology surrounding the breakpoints.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com