Sentence examples for increase in compounds from inspiring English sources

However, by quantifying compound-based target relationships, it was determined that the increase in compounds with activity against targets from different families was largely due to (assay-dependent) IC 50 measurements, rather than (assay-independent) equilibrium constants (K i values).

To answer the question if there was an increase in compound words we need to compare medieval Tang/Song/Yuan prose with Early Mandarin prose.

Several formulations combining estrogens and progestins for hormone therapy (HT) have been approved worldwide for the treatment of menopausal symptoms, yet recent data indicate a decline in their use and an increase in compounded bioidentical HT.

Thus the stimulation of insulin secretion by carbachol appears largely attributable to an increase in compound exocytosis rather than the frequency.

During movement, the rate of compound events in L5Bsupp neurons was not affected (n = 17; Figure 3I), whereas L5Benh neurons displayed a significant increase in compound EPSP rate (n = 24; Figure 3J).

The green maps indicate areas where addition of bulky steric chemical groups would presumably impose an increase in compound activity, while the yellow ones would reverse this effect, as already observed in the previous CoMFA model.

The root-mean-square deviation parameters significantly correlated in an inverse manner with the experimentally determined inhibitory constants (pKi (exp)); structural deviation decreased with an increase in compound activity and vice versa.

Although conversion of the methyl ester to the corresponding free acid 19 eliminated activity, introduction of the para-methoxy aromatic residue 25 resulted in a 10-fold increase in compound efficacy, with a BIC50 value of 6 μM.

IC 50 values are easier to determine than K i values and provide the readout of most primary biochemical assays (except single-point screening assays), which might at least in part rationalize greater target coverage and the IC 50-dependent increase in compound promiscuity across different families.

At high loading levels, DNA showed minimal increases in compounding torque, while MPP increased torque by over 20%.

We tested this strategy on the ferroptosis inducer and experimental therapeutic erastin, and observed substantial increases in compound potency.