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These changes increase the stability of the allogeneic peptide-major histocompatibility complex (pMHC) complex and increase complementarity in the TCR-pMHC interface, placing greater emphasis on recognition of the pMHC by the TCR beta-chain, evinced by an increase in shape complementarity, buried surface area, and number of TCR-pMHC contacting residues.
To further increase complementarity to mutant 5′ss, we created U1snRNAs specific for each mutation (U1F9spec; Fig. 3A).
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The second scenario presents increasing shade tolerance of the smaller species that increased complementarity, again mostly as expected.
This research investigates the value of increasing complementarity (both proximate and geographically dispersed) of wind and solar resources as a means by which electricity planners and researchers might advance electricity sustainability in Ontario.
When convergence and increased complementarity remain restricted to distinct subsets of species, then modularity will increase through a disproportionate growth of specialized motifs, creating vortexes of coevolutionary change (Thompson 2005, 2006).
For instance, new frugivores would tend to converge (be more similar in morphology) with preexisting frugivore species and share codispersed plants; in turn, selection pressures would increase the phenotypic matching of animal traits (body parts, phenology) and fruit traits, increasing complementarity between interacting partners.
At this scale, both genotypic and genetic diversity as estimated through allelic richness may lead to higher redundancy, as well as increased complementarity, synergistic or sampling effects.
In permanent pastures, grassland diversity may also reduce risks of nitrate leaching because of increased complementarity between species in N uptake and water uptake (De Deyn et al., 2009).
The addition of the 124I to the A374G(125G) mutation increased the likelihood score for the NS3 donor splice site, since the 124I mutation further increased complementarity with the spliceosomal U1 snRNA binding sequence, ACUUACCU (identical in human and mouse), which initiates splicing.
There is only very little evidence that increased phenological complementarity can have a positive effect on annual productivity in early successional forb communities, although such an effect might be stronger at low levels of species richness [48].
Using a dicistronic reporter mRNA with variant motif 1 sequences, we found that increasing the complementarity of the motif to that of yeast 18S rRNA stimulated termination-reinitiation, supporting strongly the view that intermolecular interactions are important in reinitiation on the BM2 ORF.
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