Sentence examples for increase complement from inspiring English sources

This review focuses on the classic complement pathway and the role of major complement inhibitory factors in cancer immune evasion as well as on how current protein engineering efforts are being employed to increase complement fixing or to reverse complement resistance leading to better therapeutic outcomes in oncology.

Recently, Tanhehco et al. [ 3] reported that cocaine could increase complement protein expression in isolated rabbit hearts.

Several conditions that may potentially further increase complement activity are known to uncover an underlying diagnosis of aHUS and place patients at increased risk for renal and/or extrarenal organ damage [ 1, 28, 29].

Hence, further research is still required to elucidate the impact of urea on dengue severity, which was shown previously to increase complement-fixation of dengue antigen [ 29].

Increased complement activation can be associated with enhanced viral pathogenesis.

Increased complement has been associated with enhanced inflammation and tissue destruction [24].

In this study we were only alerted to potential confounding effects by the lack of increased complement resistance conferred by the common IGR changes found in MenB isolates.

Because of this, we hypothesized that the increased complement levels in the HPAI H5N1 infected mice could be associated with the enhanced inflammation associated with these infections.

The lack of proper regulation of the AP convertase may be responsible for the increased complement activation that has been observed in DHF patients (Figure 6; Table 3).

The involvement of augmented complement activation in dengue pathophisiolgy was demonstrated by Bokisch et al. [3], however the specific mechanisms triggering the increased complement activation in dengue disease still need elucidation.

So far, it seems clear that the complement system is activated during dengue infection [11], [16]; however, it is not clear to what extent each of the three pathways (the CP, LP, and AP) contribute to the overall activation of the complement system, or what mechanisms are triggering the increased complement activation during dengue infection.