Sentence examples for increase clearance from inspiring English sources

Compounds now in clinical development are hypothesized to slow the clinical progression and pathogenesis of Alzheimer's disease (AD) by their effects to diminish production, increase clearance, or decrease aggregation of amyloid β protein.

This effect may increase clearance from the bloodstream via recognition by the immune system or disrupt the ability of the nanoparticles to be internalized by the tissue of interest [26, 27].

Loss of sUA response preceded IRs in 44 of 56 (79%) pegloticase-treated patients.Loss of responsiveness to pegloticase is associated with the development of high titer anti-pegloticase Ab that increase clearance of pegloticase and are associated with a loss of the sUA lowering effect and increased IR risk.

Visible changes from the XF-104 to production versions of the Starfighter include a longer fuselage (to accommodate the J79 engine and extra internal fuel) and a forward-retracting nose landing gear (except two-seat versions) to increase clearance for the downward-ejecting seat.

CYP2C8*11 was found to increase clearance of rosiglitazone [ 10].

Hemofiltration may increase clearance of medium to larger molecules.

Increased clearance of cortisol was recently indicated as a component in the HPA axis hyperdrive.

This is in agreement with studies showing reduced clearance rate for leptin in obese vs. lean subjects and increased clearance following an acute fasting29,30.

To put it very simply, the cellular effects resulted in both impaired mitochondrial biogenesis and increased clearance of this organelle, leading to compromised exercise capacity.

This class of compounds can cross the blood-brain barrier in rodents and induces an activation of microglia and increased clearance of amyloid-beta aggregates following low dose chronic treatments.

The contrast (circles) and contrast-weighted sensitivity (triangles) have been arranged in increasing clearance dose.