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Although a small amount of warming under the RCP2.6 scenario is expected to have a minor influence on marine pelagic biodiversity, moderate warming (RCP4.5) will increase by threefold the changes already observed over the past 50 years.
Moreover, the examination of the boundaries around the estimation point in the present meta-analysis rules out neither a deleterious effect of corticosteroids (39% risk of a greater failure rate) nor an increase by threefold in the success rate of corticosteroid treatment.
The levels of phosphorylated AMPK (pAMPK) increase by threefold 2 h after treatment.
By 2050 the prevalence of AF is expected to increase by threefold and this poses a considerable public health concern [ 2].
Despite performing frequent self-monitoring of blood glucose (SMBG) four or more times daily, severe hypoglycemic episodes increase by threefold in IIT patients regardless of the method of insulin delivery (2).
25 Several studies also showed that 95% of patients with central vein stenosis had a history of an indwelling catheter, while only 13.6% of patients without a history of an indwelling catheter developed central vein stenosis, and that repeated catheter insertions could increase by threefold the incidence of central vein stenosis in dialysis patients.
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With light/moderate cycling exercise, IVC flow increases by threefold, whereas SVC remains essentially constant.
While the general levels of hnRNPa2b1 were higher in the WT p53 cells (IP: hnRNPa2b1), the SUMOylated hnRNPa2b1 was increased by threefold in the mutp53 cells (IP SUMO1) suggesting a role for this RNA-binding protein in sorting miR-1246 into exosomes (Supplementary Fig. 7d).
Diabetes also increases stroke-related mortality [67], while the risk of dementia following a stroke is increased by threefold [68].
Cell stiffness at 10 nN had increased by threefold compared to the cell stiffness measured at 0.5 nN.
However, VEGF receptor 2 (VEGFR2) mRNA expression increased by threefold in the HRG (p < 0.01), whereas it did not significantly change in the LRG.
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