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Moreover, ChRs require a 'co-factor' (retinal) for light-triggered activity, and the sequence of processes involving ChR-mediated [Ca2+]i increase, activation of gene transcription (e.g. GLP-18) and translation may result in a slower overall response.
"We believe that people will use real-time fMRI feedback to hone cognitive strategies that will increase activation of brain regions," Dr. deCharms said.
We present new data demonstrating that combining perinatal choline-supplementation, to potentially increase activation of α7nACh receptors during development, with embryonic kynurenine manipulation is effective in attenuating cognitive impairments in adult rat offspring.
This may occur through urethral relaxation and decreased bladder compliance, both of which may increase activation of proximal urethra afferents from distension of the proximal urethra.
Therefore after the LPS insult the increase in astrogliosis was due to an increase activation of GFAP in existing cells.
However, strong binding heads inevitably clashed sterically with TM, consistent with their ability to increase activation of the thin filament by moving TM toward the open position [44].
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The downstream effect of increased PI3K is increased activation of the AKT pathway.
The R952Q variant of LRP8 increased activation of p38 mitogen-activated protein kinase by oxidized low-density lipoprotein.
Increased activation of MMP2 in turn activates proMMP9 [ 11].
It has been shown that increased activation of MT1-MMP/MMP2 complex also activates pro-MMP9 [ 29].
Therefore, the increased expression of FasL is correlated with the increased activation of the NF-κB system.
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Justyna Jupowicz-Kozak
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