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In some cases, incorrect functioning of cytokines (frequently caused by underexpression or overexpression of certain cytokine genes) directly favors development of cancer.
The evidence for the possible involvement of the 450G (m.1097G) in the incorrect functioning of bridge mt-B2c appears quite likely, since the disruption of the G809 C770 base pair by mutagenesis has been shown to be detrimental to ribosomal function (34, 35).
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The latter include impairment of cell division control systems, immunological control systems, and incorrect function of antioxidation mechanisms.
This was the case pointed out by Tripp et al. (9) where a spuriously predicted gene on the opposite strand of ribosomal RNA had been given the incorrect function of cell wall hydrolase (PF10695).
For example, gene p58 is a natural killer cell receptor and it is thought to play an important role in regulation of the immune response and cell death, so the incorrect function of this gene may cause to cancer growth.
The differences between upper limbs in children with obstetrical brachial plexus palsy may be generated by the incorrect function of paralysed muscles of upper limb as well as deficiency in correctly directed mechanical loads in the early period of bone-joint system development [ 12].
In the case of persons with mastication organ incorrect functioning, relation of articular route to the maximum opening gap of dental arches reached accordingly the level of 44 ± 11% in the case of disorders caused by improper muscles operation and 35 ± 11% in people with dysfunction caused by temporomandibular joints operation.
These mutations result in either a complete lack or reduction of protein or an incorrect functioning protein at the apical surface of epithelial cells [48].
Approximately 50% of the entries have uncertain, unknown, or incorrect function annotations because these are made by automated methods based on sequence homology.
Limitations: Incorrect use of some statistics.
Incorrect use of antibiotics accelerates AMR.
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