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Incorrect allocation of algorithms is another potential source of measurement bias in costing accounting systems.
From a health policy point of view, this may cause incorrect allocation of health resources.
Another potential source of measurement bias arise from the incorrect allocation of cost.
Furthermore, incorrect allocation to high risk reduces QoL and increases costs due to overtreatment with chemotherapy [ 43].
Thus, several technical and logistic problems such as the patients' inability to handle a mouse or incorrect allocation of patient numbers (IDs) have been successfully solved.
Assay accuracy has a large effect on cost-effectiveness, since incorrect allocation to low risk groups increases the risk of distant recurrence as a result of under treatment.
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Instead, evaluations should account for the taxonomic distance between classes, expressed as class similarities, giving partial credit to some incorrect allocations.
The simple strategy of vignette standardisation equalised and lowered the difference in the proportions of correct and incorrect trial arm allocations (from 21% compared to 2% in phase 1 to 9% compared to 6% in phase 2 for intervention arm guesses; and from 68% compared to 46% in phase 1 to 46% compared to 46% in phase 2 for control arm guesses).
"Mispricing gives incorrect signals for resource allocation, and, at worst, causes stock market booms and busts," Woolley wrote in a recent paper.
The bigger inferential concern remains, that of using common, but incorrect, statistical analyses which assume random allocation of patients.
When a simulated 5% genotyping error rate was introduced to microsatellite genotyping, map inflation (sometimes by over 50%), incorrect marker order and even occasional allocation of markers to the incorrect linkage group occurred.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com