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Here we provide evidence that histaminylation (histamine incorporation) functions as regulatory posttranslational modification.
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In addition, we investigated the incorporation of functioning minerals such as strontianite and smithsonite into the deposited layer.
They are especially suited to study the incorporation and function of ion channel proteins, where a high background resistance of the membrane is essential.
The versatility of polymer nanofibers for functionalization with biomolecules opens the door to vast opportunities for the design of tissue engineering scaffolds with even greater control over cell incorporation and function.
Though a careful titration of SPION incorporation, cellular function and MRI visualization is essential, Citrate SPIONs are very efficient intracellular magnetic labels for in vivo stem cell tracking by MRI.
Mutating this residue to alanine would remove this helix break and might potentially cause significant alterations in the incorporation and function of Pen-2 within γ-secretase.
In contrast, H3.5 incorporation may function to transiently mark TSSs to assist in the replacement with H3.3, depending on gene expression.
Therefore, great efforts have been directed toward improvement of these MAP vaccines by the incorporation of various functions into a single vaccine molecule using helper T-cell epitopes, immune-stimulant lipid moieties, or cell-penetrating peptides have been conducted.
Here, we propose an overview of nanoparticle functionalization strategies, emphasizing those that permit the incorporation of multiple functions and/or biomolecules on the surface.
Incorporation of therapeutic functions into molecular imaging contrasts plays a pivotal role in developing theranostic agents.
However, the imperfect optical properties of conventional PL imaging agents and the challenge in incorporation of therapeutic functions onto them have severely limited their abilities for use in theranostics.
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