Exact(1)
It is highly probable that kpol for rNTP incorporation by Φ29 DNAP is also significantly slower than kpol for dNTP incorporation; a decrease in kpol would conspire with the increased rNTP dissociation rate to yield the substantial discrimination exhibited by Φ29 DNAP against rNTP incorporation.
Similar(59)
This non-uniformity of alloy causes reduced indium incorporation with a decrease of channel thickness along with a thin InN binary alloy.
Thus, an increase in [H]methyl incorporation reflects a decrease in methylation.
Hydrogen incorporation leads to a decrease of the a-Si layer density.
After the incorporation of MWCNTs, a decrease in electrical resistivity of the fibers was found for MWCNT concentrations as low as 2 wt%.
Cholesterol incorporation resulted in a decrease in the CLA of the PDC-109/DMPC recombinants, which could be attributed to membrane rigidification, or to direct interaction of cholesterol with the CRAC domain of PDC-109.
In the first group of patients, the proliferation was highly significant identified by BrdUrd incorporation and by a decrease of PKH67 fluorescence.
Furthermore, SWNT incorporation also caused a decrease of action potential duration (APD) at both 50% (APD50) and 80% (APD80) of repolarization and had similar APD to native neonatal cardiomyocytes (∼120 ms of APD80).
For the B-family DNAP from bacteriophage RB69, which discriminates against rNTP incorporation by 64000-fold, kpol = 200 ± 13 s–1 for dNTP incorporation and kpol = 0.74 ± 0.2 s–1 for rNTP incorporation, a 270-fold decrease in kpol for rNTP incorporation.
Consistent with reduced BrdU incorporation, we also observed a decrease in PCNA in protein lysates of cells treated with CD147 siRNA.
These changes included inhibition of fibroblast motility and fibronectin incorporation into the substratum, a decrease in macrophage number, a reduction in MMP-2 activity and markedly less proteolysis of the ECM proteins fibronectin, laminin 1, laminin 5 and collagen 1.
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