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Three-D structure activity studies demonstrate that brain delivery can be improved >10 fold by incorporating substrate modifications that enhance carrier binding and transport.
The statistical model incorporating substrate richness contained two significant 2-way interaction terms, species richness×time and substrate richness×time (Table 1).
The statistical model incorporating substrate composition rather than substrate richness had a more complex structure, including the two 2-way interaction terms, species richness×substrate composition and substrate composition×time (Table 1).
The statistical model incorporating substrate composition rather than substrate richness had a similar structure with the two significant 2-way interaction terms, species richness×time and substrate composition×time (Table 1).
The statistical model incorporating substrate richness did not contain a significant interaction between species richness and time, but did include the significant 2-way interaction substrate richness×time as well as a single-term effect with species richness (Table 1).
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In contrast to any other reagent, it is possible to incorporate substrate-based peptide sequences.
After preparing the mixture whole mixture was preincubated at 37°C prior to initiation of the reaction by incorporating the substrate.
(41) Neurons grown in the presence of N-butanoyl mannosamine (ManNBut) were found to have shortened PSA chains, presumably due to inefficient extension of PSA polymers incorporating this substrate by polysialyltransferases. (42) In the future, biosynthetic modulation of PSA length using ManNBut might be applied to studies of PSA in neuronal development.
Select organisms incorporate the substrate and they, and their NAs, become isotopically enriched over time.
The fundamental difference between AGC method and the conventional microplate method is that AGC incorporates the substrate from the natural environment whereas the microplate method does not employ sediment.
During growth of InAsSb NWs, antimony has been incorporated from substrate which may affect electrical properties.
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