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When incorporating origin recruitment into models, several show an origin located distally on a loop, being recruited to the NM in late G1/S-phase.
A recent report [ 54] presented an ODE-based model describing the initiation of DNA replication, incorporating origin licensing, firing and the network of regulatory phosphorylation events.
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Michael Ruse claims that it is essential to incorporate origin of life resarch into Darwinism since it is a necessary condition for a scientifically and philosophically adequate definition of life (Ruse 2008, 101).
This naturalistic account even verged on incorporating the origin of human beings, although this issue is left vague.
Our genome comparison incorporating the origin of the Lepidodinium plastids strongly suggests that the endosymbiont plastid genome acquired by the ancestral Lepidodinium species has lost genes encoding proteins involved in metabolism and biosynthesis, protein/metabolite transport, and plastid division during the endosymbiosis.
If we aim to deliver to science and society a complete picture of early evolution, then at some point we have to incorporate the origin of life into the larger picture of things, too, which means linking microbial evolution to the elements on early Earth.
An outstanding lacuna in Descartes's account was his failure to incorporate the origins of living beings into this naturalistic story of creation by natural laws.
To measure microsatellite mutagenesis experimentally in epithelial cells such as HCT116, we modified the ex vivo mutational assay by incorporating the SV40 origin of replication.
Along with the name change, the character's backstory was altered to incorporate a British origin.
Additional analyses incorporating parent-of-origin effects were then undertaken that revealed strong evidence for reduced paternal transmission of the protective G allele at this locus.
Therefore, it would be more appropriate to refer to this model as a model incorporating parent-of-origin effects, and such that, it can be applied to a number of situations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com