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When tested on two different protein systems, BD was shown to generate conformations and sequences with significantly lower energies than traditional DEE (albeit at slower running times), thus confirming the potential benefit of incorporating backbone flexibility.
Incorporating backbone flexibility into the matching stage, possibly in a manner similar to the method developed by Havranek et al. [15], would likely increase the number of matches that can be found for complicated theozymes.
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In this paper, we introduce the fifth "dimension" for fold recognition by incorporating predicted backbone torsion angles (SP5).
The assembly was repeated, incorporating the backbones from these individually assembled primer-walked clones along with the shotgun reads.
In this article, we presented an algorithm for protein design that incorporates local backbone flexibility via backrub motions.
Substrate as well as product peaks were collected, vacuum-dried twice, and redissolved in order to remove deuterium incorporated into backbone amides.
One context where suppression of LINE-1 by nRTIs may result in side-effects is in the treatment HIV-1 infection by an antiretroviral (ARV) regimen incorporating an nRTI backbone.
The approach uses a united virtualization of optical and server resources that collaboratively incorporates the optical backbone into Data Centers.
Phosphorus was incorporated within the backbone of the epoxy resin and not used as an additive.
There have been steady improvements in the design of organic radical polymers, in which radicals are incorporated into the backbone and/or as pendant groups.
We have developed biodegradable antioxidant copolyoxalate, in which HBA is chemically incorporated into its backbone for the treatment of oxidative stress-related diseases.
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