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The purpose of our study was to evaluate whether recently published translational research studies that examined biomarkers for diagnosis, disease activity, and prognosis in systemic autoimmune diseases incorporated study-design features important for valid clinical associations.
The CONCORD protocol incorporated studies designed to explain the international variations in survival.
Fewer than one half of studies incorporated study-design features important for valid clinical associations.
We imposed no restrictions for publication date, publication format or language and incorporated no study design filters.
Comparator analgesics incorporated into study design were ketorolac IV or IM (30 mg or 60 mg) in four studies and morphine (4 mg IV) in three studies.
CPGs are systematic guidelines devised to guide healthcare providers and patients in decision making processes [ 8], and discussions for expert consensus on appropriate clinical practice patterns should precede controlled trials to be incorporated in study design and CPG construction.
Other process variables, such as arousal and boredom, should also be incorporated to study designs in order to reveal more on the nature of how music affects driving.
The study was carried out within a qualitative approach which incorporated a collective case study design.
The study design incorporated useful infrastructure recommended by the Fédération Internationale de Médecine Manuelle (FIMM) including protocol agreement steps prior to conducting the formal interexaminer reliability study with the goals of attaining >80% interexaminer agreement and kappa values >0.6 for each cardinal plane.
Study design incorporated comparison of 10 Vietnam War veterans with PTSD diagnosis to 10 Vietnam War veterans with no mental disorder diagnosis on P3 components in a series of two oddball tasks (trauma-relevant threat, trauma-irrelevant threat) counterbalanced for order.
Our mixed methods study design incorporated: stakeholder analysis; survey design and implementation; activity-based cost accounting techniques; and an expert panel to review and validate our results.
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