Each application depends on incorporated functionality.
As such, we raised the question whether incorporated functional RNA moieties, including RNA fluorogenic aptamers, and therapeutic RNA molecules would fold into their functional 3D structures with preserved functionalities resulting in multifunctional RNA nanoparticles.
Exposure of the polymer under DC glow discharges has essentially incorporated oxygen functionalities on the polymer surface as detected by ESCA.
One-dimensional permeation studies showed that the gel with maximum incorporated chemical functionality had the lowest diffusion coefficient, which was one to two orders of magnitude lower than all other gels studied.
Finally, we examined gene/protein interaction databases [ 24- 28] and incorporated their functionality into Autworks, as these repositories mainly focus on general cellular interactions without disease-context.
Using this information, we previously designed and synthesized ketomethylene inhibitors that incorporated the above functionalities either alone or in combination and showed that the incorporation of the P2 aspartate residue and N-protecting group resulted in a 1000-fold shiftowardsds N-selectivity [ 33].
When Flock got started (and funded), it was easy to defend the need for a Web browser that incorporated tons of functionalities that catered to a new breed of online services and applications (remember Web 2.0?) and their power users.
We are really excited about the potential reach of the new product, not just to individuals but to businesses too, for which we have incorporated conference call functionality into the letsroam service.
56, 127, 128 Fillers, such as nanoparticles 129– 131 or liquid crystalline polymers, 132 may also be incorporated to impart functionality, such as optical or mechanical properties.
Because most of the telemonitoring systems that are used in the Netherlands have some CDSS functionality incorporated (e.g., advice to take action based on incoming alerts) it seems justified to assume that 30% of the respondents have more or less experiences in using CDSS and therefore responded to the questionnaire based on practical experiences.
