The population genetics model (Fig. S1) incorporated estimates of the key biological parameters for H. armigera to simulate changes in the frequency of two resistance alleles owing to selection by Cry1Ac/Cry2Ab cotton.
For the prior distribution of r, we incorporated estimates from previous studies about CNVs.
As the prior study had not incorporated estimates of global and local ancestry, we wished to analyze these SNPs with adjustment for ancestry and isoform number.
We incorporated estimates of effectiveness into an incremental cost-effectiveness analysis performed from a limited societal perspective.
Finally, we incorporated estimated risk for death per patient, a rate that in turn would reduce the number of admitted patients at any 1 time.
In this way, the quality of the incorporated estimates can be increased over iterations.
On the basis of this value, the value of r (distance between W14 and incorporated AEDANS) was estimated for the mutant proteins under different conditions.
**Sensitivity analyses incorporated range of utility weights, along with low and high estimates for life-expectancy after TB disease, and low and high estimates of TB related mortality.
Relative to those produced by the method with misclassification incorporated (Analysis 1), the naive analysis (Analysis 2) yields attenuated point estimates for β a and β as, and leads to an inflated estimate of β s.
To account for overdispersion in the count data, extra-Poisson variability was modeled and incorporated into estimates of standard errors.[24] Parameter estimates were transformed to rate ratios.
