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Finally, our study design is robust as it is one of the few to have incorporated a sample size calculation a priori and pretested all questions with a panel of content experts.
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Thus by restricting the number of bins we implicitly incorporate a sample-size dependent penalty for over-fitting of the data.
The study incorporated a large sample size over a long time span.
The strengths of this protocol are that it tests an innovative, internet-based treatment that targets fundamental social cognitive deficits in schizophrenia, employs a highly sensitive and extensive battery of functional outcome measures, and incorporates a large sample size in an RCT design.
Additional studies are encouraged which incorporate a larger sample size and PLR as a primary end-point such that the beneficial impact of the use of HB sperm in ICSI can be further evaluated.
The design of the RCT incorporates a large sample size with adequate power to detect the primary outcomes, and a long follow-up period to observe meaningful improvements in patient health outcomes [ 18, 19].
Many of these limitations, however, can be addressed in the future with prospective, longitudinal validation incorporating a larger sample size and multi-center collaboration.
This level of variability was incorporated into a statistical model, based on the current study design and a sample size of 20 patients.
We have a sample size of one.
"It's too small a sample size," McClure said.
This gave me a sample size well above 200.
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