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Further adjustment of the model to incorporate expression of individual markers or the molecular subtype resulted in minimal change in the survival benefit conferred by screen detection.
The basic model could also incorporate expression of the α6 subunit, assuming that additional gene-specific factors contribute to produce a different tissue-specific expression profile.
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Macrophage phenotype was assessed using double stain immunohistochemistry incorporating expression of an intracellular enzyme of function.
Upstream Regulator Analysis in IPA incorporates expression of downstream target genes from the experimental dataset and compiled knowledge of reported relationships between regulators and their known target genes within IPKB.
Considering that we did not incorporate expression information of miRNAs, the establishment of such statistically detectable associations underscores the predictive potential of our approach.
Before taking promising effector candidates to experimental validation, one can incorporate expression data of in planta infection such as microarray or RNAseq data.
If the CMAP methodology is accepted as a useful discovery tool then it is natural to look for ways of extending it to incorporate expression data from a wider set of experiments.
The past year has seen significant advances in the number, scope and quality of studies that incorporate expression profiling experiments.
Highly expressing cells were isolated by FACS using a MoFlo cell sorter (Beckman Coulter Incorporated), and expression of Nullbasic was confirmed by western blot analysis.
Our results here not only explain in part the apparent redundancy in the DNA binding specificity of transcription factors – TFs with similar binding have dissimilar expression pattern – but also underscore the importance of incorporating the expression of the transcription factor genes in the analysis of transcriptional regulation.
Thus, clinicians should incorporate explicit expressions of empathy, which help to control emotional fluctuations and distractions, and thereby enhance cognitive processing of important clinical information.
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